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目的:了解淮安地区出生缺陷发生情况,发现影响出生缺陷的可疑因素,制定有效预防、干预措施。方法:对2005～2007年淮安市各监测医院出生的围产儿资料进行回顾性分析,采用2χ检验分析相关因素。结果:出生缺陷发生率为3.19‰,出生缺陷的发生与遗传、环境、孕母年龄、出生性别等因素有关。结论:做好孕前、孕期保健,常规行唐氏筛查,孕中期常规行彩超排畸,避免缺陷儿进入围产期,可以降低出生缺陷发生率。
Objective: To understand the occurrence of birth defects in Huaian area, to find out the suspicious factors that affect birth defects and to develop effective prevention and intervention measures. Methods: The data of perinatal infants born in monitoring hospitals in Huaian from 2005 to 2007 were retrospectively analyzed. The 2χ test was used to analyze the related factors. Results: The incidence of birth defects was 3.19 ‰. The incidence of birth defects was related to the factors such as genetics, environment, mother’s age, and sex at birth. Conclusion: Pre-pregnancy, prenatal care, routine screening Down’s screening, the second trimester of conventional color ultrasound row to prevent defects in children into the perinatal period, can reduce the incidence of birth defects.