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碳酸锂具有较强的抗躁狂作用,目前在临床上应用广泛,此药致桡神经麻痹尚属罕见,现将我院服碳酸锂致桡神经麻痹2例报告如下: 例1:陈某,男,21岁,因兴奋话多吹嘘8天入院。诊断为单次发作躁狂症。给予碳酸锂治疗,剂量为0.75/d,HPD10mg肌注日2次,以控制兴奋改善睡眠。5天后睡眠改善停用HPD,碳酸锂加量至1.5/d,同时加服氯氮平150mg/d,住院第26天病人出现右手腕不能背屈,手指不能伸直,手腕下垂麻木,握物可。即停服碳酸锂加服VitB_(12),VitB_1、21-金维他、强的松治疗。3天后右手麻木现象好转,因家属要求转院治疗,故出院。
Lithium carbonate has a strong anti-mania effect, is currently widely used in clinical practice, the drug caused radial nerve paralysis is still rare, now our hospital service lithium carbonate induced radial nerve paralysis in 2 cases are reported as follows: Example 1: Chen, Male, 21, admitted more than 8 days for admission due to excitement. Diagnosed as a single episode mania. Give lithium carbonate treatment, a dose of 0.75 / d, HPD10mg intramuscular injection 2 times to control the excitement to improve sleep. 5 days after sleep disabling HPD, lithium carbonate dosage to 1.5 / d, plus service clozapine 150mg / d, on the 26th day of hospitalization patients can not dorsiflexion of the right wrist, fingers can not be straightened, writhing wrist numbness, hold the object can. That is to stop taking lithium carbonate plus serving VitB_ (12), VitB_1, 21-Golden Vita, prednisone treatment. 3 days after the numbness of the right hand improved, due to transfer of family members required treatment, it was discharged.