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目的：观察羟丁酸钠对清醒患者经鼻盲探气管插管时镇静与健忘的作用。方法：随机将全麻病人分为 Ａ 组（羟丁酸钠）， Ｂ组（英诺氟） ，记录术前术后镇静健忘评分，统计学处理组间评分结果。结果：插管前静脉给予羟丁酸钠，术前镇静及术后健忘评分与常规氟芬组有非常显著性差异（ Ｐ＜ ０．００１）。结论：羟丁酸钠具有较好的镇静、健忘作用，减轻清醒患者因经鼻腔插管操作所引起医源性心理伤害的应激反应。
Objective: To observe the effect of sodium oxybate on sedation and forgetfulness during nasal blind tracheal intubation in awake patients. Methods: Anesthesia patients were randomly divided into group A (sodium oxybate) and group B (prednisolone). The scores of sedation and forgetfulness before and after surgery were recorded, and the score between the groups was statistically analyzed. Results: Pre-intubation intravenous sodium oxybate, preoperative sedation and postoperative forgetfulness scores were significantly different from those of conventional fenofibrate group (P <0.001). CONCLUSION: Sodium oxybate has a good effect of sedating and forgetfulness and alleviating the stress response of awake patients caused by iatrogenic intubation.