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一、乙型肝炎表面抗原(HBsAg)HBsAg 系乙型肝炎病毒(HBV)的外壳,在肝细胞浆内质网池中复制装配,剩余的 HBsAg释放至体液与组织中,其血清中的含量可达10~3,比病毒本身多10~6倍,较易测得.血清内检得 HBsAg 表示体内存在着 HBV,标志着一定的传染性.将 HBsAg 阳性血液稀释至10~(-4)可导致黄疸型肝炎,稀释10~(-5)～10~(-7)使约50%受试者感染后40～120天血中出现 HBsAg.滴度高传染性强.HBSAg 阳性见于:(1)急性乙型肝炎的潜伏期或急性期,大多仅短期阳性.(2)慢性 HBsAg携带者(健康携带者或有免疫缺陷的携带者).(3)HBV 所致的慢性肝病:迁延型和慢性活动性肝炎、肝炎后肝硬化或原发性肝癌.HBsAg 的动态检测可协助早期诊断及判断预后.
First, the hepatitis B surface antigen (HBsAg) HBsAg Department of Hepatitis B virus (HBV) shell, in the cytoplasmic cytoplasm of hepatocyte cytoplasm replication assembly, the remaining HBsAg released into the body fluids and tissues, the serum content can be Up to 10 ~ 3, 10 ~ 6 times more than the virus itself, easier to measure.Human serum HBsAg indicates the presence of HBV in the body, marking a certain contagious.Can be diluted HBsAg-positive blood to 10 ~ (-4) Lead to jaundice hepatitis, dilute the 10 ~ (-5) ~ 10 ~ (-7) so that about 50% of the subjects infected 40 ~ 120 days after the onset of HBsAg in blood. (2) Chronic HBsAg carriers (healthy carriers or carriers with immunodeficiency). (3) Chronic liver diseases caused by HBV: Persistent and chronic Active hepatitis, posthepatitic cirrhosis or primary liver cancer.HBsAg dynamic detection can help early diagnosis and prognosis.