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目的:研究膳食纤维、粪便中的丁酸含量与结肠腺瘤性息肉的关系。方法:选取所在医院收治的患者共150例,符合入选和排除标准,评估膳食纤维评分及测定肠道粪便中丁酸的含量,判断二者的相关性;并将患者分为无息肉组、非腺瘤性息肉组及腺瘤性息肉组,比较膳食纤维评分及粪便中的丁酸含量在不同分组中的差异。结果:膳食纤维评分与粪便中丁酸的含量呈正相关(n R=0.849);膳食纤维评分在无息肉组、非腺瘤性息肉组及腺瘤性息肉组中比较差异有统计学意义(n P非腺瘤性息肉组>腺瘤性息肉组;丁酸在无息肉组、非腺瘤性息肉组及腺瘤性息肉组中比较差异有统计学意义(n P非腺瘤性息肉组>腺瘤性息肉组。n 结论:膳食纤维影响粪便中的丁酸含量,且二者对结肠腺瘤性息肉的产生可能有一定的作用。“,”Objective:To study the correlation between the dietary fiber and the content of fecal butyric acid, and the relationship with colonic adenomatous polyps.Methods:A total of 150 patients screened by inclusion and exclusion criteria were enrolled in this study, the dietary fiber score and the content of fecal butyric acid were evaluated to determine the correlation between the two. The patients were divided into non-polyp group, non-adenomatous polyp group and adenomatous polyp group, the dietary fiber score and the content of fecal butyric acid in different groups were compared.Results:Dietary fiber score was positively correlated with the content of fecal butyric acid (n R=0.849). There were statistically significant differences in dietary fiber scores among the three groups (n P<0.01), with the score from high to low as the non-polyp group, non-adenomatous polyp group and adenomatous polyp group. There were statistically significant differences in the content of fecal butyric acid among the three groups (n P<0.05), and the contents from high to low as non-polyp group, non-adenomatous polyp group, adenomatous polyp group.n Conclusion:Dietary fiber affects the content of fecal butyric acid, and both of them may play a certain role in the generation of colorectal adenomatous polyps.