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目的探讨咳嗽变异型哮喘(CVA)的临床特点及治疗效果。方法对我院2009年12月至2011年4月收治的咳嗽变异型哮喘患者51例的临床资料进行回顾性总结分析。结果感染因素及理化环境因素是CVA重要的发病因素,本组用药1周后症状完全缓解43例(84.3%),2周后症状显著缓解6例(11.8%),所有病例均在4周后症状逐渐消失,随访观察1个月后无明显发作。结论持续性的炎症反应与气道高反应性是CVA的病理生理基础,早期干预并给予以激素长期吸入为主要措施的综合性治疗措施,可获良效。
Objective To investigate the clinical characteristics and therapeutic effect of cough variant asthma (CVA). Methods The clinical data of 51 patients with cough variant asthma admitted in our hospital from December 2009 to April 2011 were retrospectively analyzed. Results The factors of infection and physico-chemical factors were the important factors of CVA. Symptoms were relieved completely in 43 patients (84.3%) after 1 week and in 6 weeks (11.8%) after 2 weeks. All the patients were in 4 weeks Symptoms gradually disappear, followed up for 1 month without significant attack. Conclusions The persistent inflammatory response and airway hyperresponsiveness are the pathophysiological basis of CVA. Early intervention and long-term inhalation of hormones are the main measures for comprehensive treatment, and good results can be obtained.