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目的:探讨口服华法林预防房颤并发脑卒中的临床疗效。方法:选择收治的58例房颤患者,其中男38例,女20例,随机分成对照组和观察组各29例,对照组常规给予病因治疗,控制血压、血糖、纠正心衰,控制心室率等,并服用阿司匹林100mg,1次/日。治疗组在对照组治疗的基础上,化验凝血四项后入选,服用华法林片(2.5mg/片),从0.625～1.25mg/日开始,调整INR在2.0～3.0,最大量6.25mg/日。结果:经过治疗,治疗组29例中出血并发症3例(10.3%),并发脑卒中2例(69.%);对照组29例,血并发症11例(37.9%);并发脑卒中10例(34.5%)。结论:口服华法林预防房颤并发脑卒中的疗效显著。
Objective: To investigate the clinical efficacy of oral warfarin in preventing stroke complicated by atrial fibrillation. Methods: Fifty-eight patients with atrial fibrillation were selected, including 38 males and 20 females. The rabbits were randomly divided into control group and observation group, with 29 cases in each group. The control group was given routine etiological treatment to control blood pressure and blood sugar, correct heart failure and control ventricular rate And so on, and taking aspirin 100mg, 1 times / day. The treatment group in the control group based on the treatment of coagulation after four were selected, taking warfarin tablets (2.5mg / tablet), starting from 0.625 ~ 1.25mg / day, adjust the INR at 2.0 to 3.0, the maximum amount of 6.25mg / day. Results: After treatment, bleeding complications in 29 cases (10.3%) and stroke in 2 cases (69%) were observed in 29 cases in control group, 29 cases in control group and 11 cases (37.9% Example (34.5%). Conclusion: The effect of oral warfarin in preventing stroke complicated with atrial fibrillation is significant.