Hepatitis C virus non-structural 5A protein can enhance full-length core protein-induced nuclear fac

• 作 者: Qing-Jiao Liao Lin-Bai Ye Khal
• 机 构: StateKeyLaboratoryofVirology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年41期
• 关键词: 丙型肝炎病毒 核因子-KB 活化作用 病毒感染 HCV NS5A Core protein NF- k B
• 基金项目: Supported by the Ph D Program Foundation of Ministry of Education of China, No. 20010486015. ACKN0WLEDGMENTS The authors thank Dr. Charles M Rice （University of Washington） for providing pBRTM/HCV1-30

<正>AIM: To study the effects of hepatitis C virus (HCV) core and non-structural 5A (NS5A) proteins on nuclear factor-κB (NF-κ@B) activity for understanding their biological function on chronic hepatitis caused by HCV infection. METHODS: Luciferase a