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【目的】评价肌钙蛋白I(cTn I)定性检测在急诊科诊断急性心肌梗死(AMI)的应用价值。【方法】对832例因急性胸痛疑诊为AMI的患者,于就诊即刻行cTn I定性检测,由确诊为心肌梗死和非心肌梗死患者的测定结果计算出cTn I检测对诊断心肌梗死的灵敏度和特异性,并按病人胸痛发作至入院就诊时间进行比较分析。【结果】在胸痛发作6 h内,cTn I定性检测的灵敏度为40.2%,特异性为97.5%,其灵敏度显著低于胸痛发作6 h后(P<0.01)。【结论】cTn I定性检测的阳性结果可为急性胸痛患者诊断AMI提供较为准确的诊断信息,但其阴性结果对排除心肌梗死的价值不大,尤其在胸痛发作6 h内。
【Objective】 To evaluate the value of qualitative detection of cTn I in the diagnosis of acute myocardial infarction (AMI) in the emergency department. 【Methods】 A total of 832 patients with suspected AMI due to acute chest pain were examined qualitatively with cTn I at the time of diagnosis. The sensitivity of cTn I test to diagnosis of myocardial infarction was calculated from the results of the patients with confirmed myocardial infarction and non-myocardial infarction. Specificity, and according to the patient’s chest pain onset to hospital treatment time for comparative analysis. 【Results】 The sensitivity of qualitative detection of cTn I was 40.2% and the specificity was 97.5% within 6 hours after onset of chest pain. The sensitivity of cTn I was significantly lower than that of 6 hours after onset of chest pain (P <0.01). 【Conclusion】 The positive results of qualitative detection of cTn I can provide more accurate diagnostic information for the diagnosis of AMI in patients with acute chest pain. However, the negative results have little value in the treatment of myocardial infarction, especially within 6 h of chest pain.