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为了研究中药和针灸治疗性中风及其后遗症的机理,有必要制作缺血性中风的动物模型。该种模型一般采用结扎有关脑动脉或注入异物等方法。我们则用家兔血液中的纤维白蛋,造成家兔缺血性中风的动物模型。现报道如下。材料和方法选择青紫兰家兔60只,体重为2～3kg,雌雄不拘。氯胺酮麻醉,常规手术,颈外动脉远侧端结扎,近结扎处向颈总动脉方向剪一“V”形口,插入一塑料管至颈内、外动脉分义处。夹闭右侧颈总动脉,将提取的纤维蛋白加工成1mm左右的栓子并兰染,制成生理盐水悬浮液(200mg/10ml),注入
In order to study the mechanism of traditional Chinese medicine and acupuncture for treating stroke and its sequelae, it is necessary to make an animal model of ischemic stroke. This type of model is generally used to ligation related to cerebral arteries or injection of foreign bodies and other methods. We used fiber white eggs in rabbit blood to create an animal model of ischemic stroke in rabbits. The report is as follows. Materials and Methods 60 green-blue rabbits weighing 2 to 3 kg were selected. Ketamine anesthesia, routine surgery, ligation of the distal end of the external carotid artery, near the ligation point, cut a “V”-shaped mouth in the direction of the common carotid artery, and insert a plastic tube into the internal and external carotid artery. The right common carotid artery was clamped, and the extracted fibrin was processed into a 1 mm plug and blue stained to prepare a physiological saline suspension (200 mg/10 ml).