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尽管以蛋白为基础的抗肿瘤坏死因子-α(TNF-α)治疗风湿性关节炎取得了一些成就,然而与蛋白药物相关的问题是非肠道给药可能形成抗药抗体,因而需要抗TNF-α治疗的其他途径。从多种草药提取物中筛选具抗TNF-α分泌作用的药物,发现三七Panax notoginseng(Burk.)F.H.Chen正丁醇提
Although some achievements have been made in the treatment of rheumatoid arthritis with protein-based anti-tumor necrosis factor-alpha (TNF-alpha), the problem associated with protein drugs is that parenteral administration may form anti-drug antibodies and therefore anti-TNF- Other ways of alpha therapy. Screening of drugs with anti-TNF-α secretion from various herbal extracts found Panax notoginseng (Burk.) F.H. Chen n-butanol extraction