Effect of nicardipine on learning and memory in mice

• 作 者: 吴树勋 林瑞华 袁凤燕 杜玉民 鲍春和 陈子明
• 机 构: Hebei Academy of Medical Sciences, Shijiazhuang 050021, ,Hebei Academy of Medical Sciences, Shijiazh
• 出 处: Acta Pharmacologica Sinica
• 发表日期: 1996年01期
• 关键词: capable retrieval impairment creased avoidance alcohol antag showing

AIM: To study if nicardipine could improve learning and memory in mice. METHODS AND RESULTS: Nicardipine (0.5mg·kg~(-1)or 0.2 mg·kg~(-1), po) was shown to improve learning and memory in Y mize in mice, which increased passive avoidane response. Nicardipine was capable of antagonizing pentobarbital (15 mg·kg~(-1), ip)-in

AIM: To study if nicardipine could improve learning and memory in mice. METHODS AND RESULTS: Nicardipine (0.5 mg · kg -1 (0.2 mg · kg -1), po) was shown to improve learning and memory in Y Mize in mice, which increased passive avoidane response. Nicardipine was capable of antagonizing pentobarbital (15 mg · kg -1, ip) -in