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【目的】动态观察医院出生缺陷发生的消长情况及影响出生缺陷的可疑因素,为制定出生缺陷的预防措施以及评价其效果提供依据。【方法】采用横断面调查的方法,依据1996~2006年所有监测医院的围产儿总例数,出生缺陷儿的总例数,分析宝鸡市1996~2006年出生缺陷发生率及发展趋势;并对2007年的资料进行两组比较研究,统计分析影响出生缺陷的高危因素。【结果】宝鸡市出生缺陷发生率总体呈下降趋势,出生缺陷的发生随孕母文化程度增高而降低;孕早期服药及患病情况对出生缺陷有较大影响;孕产妇的年龄、胎数及胎儿性别为影响新生儿出生缺陷的高危因素。【结论】通过加强三级预防措施,可以降低缺陷儿发生率。
【Objective】 To dynamically observe the growth and decline of birth defects and the suspicious factors that affect birth defects in hospitals, and provide evidences for the prevention of birth defects and the evaluation of their effects. 【Methods】 By means of cross-sectional survey, the total number of perinatal children and the number of birth defects in all monitoring hospitals from 1996 to 2006 were analyzed. The incidence and development trend of birth defects in Baoji from 1996 to 2006 were analyzed. 2007 data were compared between the two groups, statistical analysis of the risk factors of birth defects. 【Results】 The incidence of birth defects in Baoji City generally showed a decreasing trend. The incidence of birth defects decreased with the increase of pregnant women’s education level. Taking medicine and illness in early pregnancy had a significant impact on birth defects. The age, number of births, Fetal gender as a risk factor for neonatal birth defects. 【Conclusion】 By strengthening tertiary prevention measures, the incidence of defective children can be reduced.