论文部分内容阅读
目的：回顾性分析睾丸精原细胞瘤的治疗效果，探索综合治疗的原则。方法：总结中山医科大学肿瘤医院１９７５年至１９９０年收治的１６３例睾丸精原细胞瘤，其中单纯手术４例，术后化疗２２例，术后放疗５２例，术后放疗加化疗８５例。以直接法计算生存结果。结果：总５年生存率７３．６２％；Ⅰ、Ⅱ、Ⅲ（Ⅳ）期分别为８４．３７％、６４．２９％和２７．２７％。单纯手术４例（Ⅰ期）区域淋巴结转移５０％（２／４）；术后综合放疗可有效控制区域淋巴结转移，综合多程化疗可有效控制远处转移。结论：睾丸精原细胞瘤术后常规放疗综合２疗程以上化疗可有效提高治疗效果。
Objective: To retrospectively analyze the therapeutic effects of testicular seminoma and explore the principles of comprehensive treatment. Methods: A total of 163 cases of testicular seminoma were enrolled in Tumor Hospital of Sun Yat-sen University of Medical Sciences from 1975 to 1990, including 4 cases of simple operation, 22 cases of postoperative chemotherapy, 52 cases of postoperative radiotherapy, and 85 cases of postoperative radiotherapy and chemotherapy. Calculate survival results by the direct method. Results: The overall 5-year survival rate was 73.62%; the I, II, and III (IV) periods were 84.37%, 64.29%, and 27.27%, respectively. 4 cases (stage I) of regional lymph node metastasis were treated with surgery alone, 50% (2/4); postoperative comprehensive radiotherapy can effectively control regional lymph node metastasis, and comprehensive multi-pass chemotherapy can effectively control distant metastasis. Conclusion: The conventional radiotherapy for postoperative testicular seminoma is a comprehensive treatment of more than two courses of chemotherapy can effectively improve the treatment effect.