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目的:观察糖脂双调方治疗糖尿病前期的临床疗效。方法:选取糖尿病前期患者68例,随机分为治疗组和对照组各34例。两组患者均给予适当生活方式干预及健康教育,治疗组在此基础上加用自拟糖脂双调方治疗,6个月后观察两组患者干预前后空腹血糖(FBG)及餐后2 h血糖(PBG)、糖化血红蛋白(Hb A1c)、血脂(TG、TC、HDL-C、LDL-C)等。结果:两组患者治疗后FBG、2 h PG、Hb A1c均较治疗前下降(P<0.05或P<0.01);两组方法均能改善患者血脂代谢,治疗组TG降低明显,HDL-C升高,与治疗前比较,差异有统计学意义(P<0.05);治疗组疗效优于对照组,差异有统计学意义(P<0.05)。结论:糖脂双调方结合生活方式干预,能降低糖尿病前期患者血糖及血脂,预防糖尿病的发生。
Objective: To observe the clinical efficacy of Diabetes Double Tone Formula in the treatment of pre-diabetes. Methods: Sixty-eight patients with pre-diabetes were randomly divided into treatment group (34 cases) and control group (34 cases). Two groups of patients were given appropriate lifestyle intervention and health education, the treatment group on the basis of the use of self-made glycolipid double transfer prescription treatment, 6 months after the observation of two groups of patients before and after fasting blood glucose (FBG) and postprandial 2 h Blood glucose (PBG), Hb A1c, lipids (TG, TC, HDL-C, LDL-C) and so on. Results: FBG, 2 h PG and Hb A1c in both groups were significantly lower than those before treatment (P <0.05 or P <0.01). Both of the two methods could improve the blood lipid metabolism, and the TG in the treatment group decreased significantly. The levels of HDL-C ascending The difference was statistically significant (P <0.05). The curative effect of the treatment group was better than that of the control group, the difference was statistically significant (P <0.05). Conclusion: Combined with lifestyle intervention, glycolipid double prescriptions can reduce blood glucose and blood lipid in pre-diabetic patients and prevent the occurrence of diabetes.