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流体动力平衡系统(HBS~(TM))是一类能延长药物在胃肠道中停留时间的口服剂型(胶囊或片剂)。它由药物和能形成凝胶的亲水胶体所组成,能浮于胃内容物之上。它不仅延长药物在胃肠道中的停留时间,而且使之保持在胃肠道的某一部位,使药物最大限度地以溶液形式到达吸收部位,有利于吸收。药物能处于完全控制的情况下,在胃液pH或处方组成控制的pH下,从胶囊中溶出和释放。本剂型的特征对很多不溶于肠液的药物、
Hydrodynamic Balance System (HBS ™) is a family of oral dosage forms (capsules or tablets) that extend the dwell time of drugs in the gastrointestinal tract. It consists of a drug and a gel that forms a hydrophilic colloid that floats on the stomach contents. It not only prolongs the residence time of the drug in the gastrointestinal tract, but also keeps it in a certain part of the gastrointestinal tract, allowing the drug to reach the absorption site in the form of a solution to the maximum extent, which is good for absorption. The drug can be released and released from the capsule at full pH control at the pH of the gastric fluid or at the pH controlled by the formulation. The characteristics of this form of many insoluble in intestinal fluid drugs,