论文部分内容阅读
人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)是一种早期胚胎滋养球细胞和胎盘滋养层合体细胞分泌的、由α及β2个亚基以非共价健结合的糖蛋白激素。本研究发现在受精后第3日70.8%(34/42)和第5日98.1%(53/54)的单个胚胎培养液中均可检测到胚胎源性hCG,其浓度与第5天囊胚评分呈正相关(r=0.525,P<0.001)。胚胎源性hCG妊娠组显著高于非妊娠组,分别为2.110±0.435 mIU/ml及1.706±0.445 mIU/ml(P=0.044),提示培养液中胚胎源性hCG水平与胚胎发育、评分及着床潜能正相关。
Human chorionic gonadotrophin (hCG) is a glycoprotein hormone secreted by early embryonic feeder cells and placental trophoblast cells and non-covalently bound by α and β 2 subunits. This study found that embryo-derived hCG could be detected in 70.8% (34/42) on day 3 and 98.1% (53/54) on day 5 in embryo-derived hCG, The scores were positively correlated (r = 0.525, P <0.001). The embryo-derived hCG pregnancy group was significantly higher than the non-pregnant group, 2.110 ± 0.435 mIU / ml and 1.706 ± 0.445 mIU / ml (P = 0.044), suggesting embryo-derived hCG levels and embryonic development, score and Bed potential is positively correlated.