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目的对慢性心力衰竭(CHF)患者的治疗及预后进行分析。方法选择CHF患者80例,随机分为两组,对照组40例,常规抗心衰治疗(强心、利尿、扩血管和血管紧张素转换酶抑制剂ACEI或血管紧张素Ⅱ受体拮抗剂);观察组40例,在常规抗心衰治疗基础上,加用卡维地洛,观察4周,随访l8个月。治疗前后对比心功能、血压、心率、左室收缩末内径(LVESD)、左室射血分数(LVEF)的变化。结果在改善心脏结构和心功能,减少住院次数和心率,观察组优于对照组,差异均有统计学意义(P<0.05)。结论β受体阻滞剂治疗CHF,能更好地改善心功能,减少CHF患者临床事件的发生,是一种安全、有效的方法。
Objective To analyze the treatment and prognosis of patients with chronic heart failure (CHF). Methods Eighty patients with CHF were randomly divided into two groups: control group (n = 40) and conventional anti-heart failure treatment (cardiac, diuretic, vasodilator and angiotensin-converting enzyme inhibitor ACEI or angiotensin II receptor antagonist) ; Observation group of 40 cases, in the conventional anti-heart failure treatment based on the use of carvedilol, observed for 4 weeks, followed up for l8 months. The changes of cardiac function, blood pressure, heart rate, left ventricular end-systolic diameter (LVESD) and left ventricular ejection fraction (LVEF) before and after treatment were compared. Results The improvement of cardiac structure and cardiac function, reduction of hospitalization frequency and heart rate were observed in the observation group and the control group. The differences were statistically significant (P <0.05). Conclusion β-blocker treatment of CHF, can better improve cardiac function, reduce the occurrence of clinical events in patients with CHF, is a safe and effective method.