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混合结缔组织病(Mixed Connective TissueDisease,MCTD)系一种特殊类型罕见的结缔组织病。1972年Sharp报道以来,国外已报道近300例,其中儿童50余例,国内儿科报道极少。本文报告1 例M(?)TD伴有桥本氏甲状腺炎及心包积液,确诊后及时应用激素治疗,疗效显著。 女,11 10/12岁。住院号17762。因阵发性肢端苍白8个月,颈部肿大7个月伴心动过速入院。患儿8个月前运动后出现四肢末端、舌尖,嘴唇阵发性苍白,发冷,5～10次/日,每次5～10分钟后自行缓解,
Mixed connective tissue disease (Mixed Connective Tissue Disease, MCTD) is a special type of rare connective tissue disease. Sharp reported since 1972, nearly 300 cases have been reported abroad, of which more than 50 cases of children, domestic pediatric reports rarely. This article reports a case of M (?) TD with Hashimoto’s thyroiditis and pericardial effusion, timely diagnosis and treatment of hormone therapy, the effect was significant. Female, 11 10/12 years old. Hospital number 17762. Due to paroxysmal extremity pale 8 months, neck enlargement of 7 months with tachycardia admitted. 8 months after the onset of children with limb extremities, tongue, paroxysmal pale lips, chills, 5 to 10 times / day, each 5 to 10 minutes after the self-remission,