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目的探讨医用生物蛋白胶在防治乳腺癌改良根治术后皮下积液的方法和疗效。方法将94例行乳腺癌改良根治术的患者随机分成两组,实验组应用医用生物蛋白胶组46例,对照组48例未使用医用生物蛋白胶,观察术后两组第1天引流量、总引流量及皮下积液发生的情况,并对两组进行统计分析。结果医用生物蛋白胶组术后第1天引流量为(83.2±10.9)ml,较对照组的(190.2±36.5)ml明显减少,差异具有统计学意义(P<0.05),实验组术后总引流量为(180.8±30.1)ml,明显低于未使用生物蛋白胶组的(448.1±84.2)ml,差异具有统计学意义(P<0.05),实验组皮下积液的发生率为10.87%(5/46),明显低于未使用生物蛋白胶组的33.33%(16/48)。结论医用生物蛋白腔能有效控制创面渗血、封闭淋巴管,减少创面引流量,降低皮下积液发生率,在防治乳腺癌改良根治术后皮下积液方面具有良好的临床应用价值。
Objective To investigate the method and efficacy of medical bio-protein glue in preventing and treating subcutaneous effusion after modified radical mastectomy for breast cancer. Methods Ninety-four patients undergoing modified radical mastectomy were randomly divided into two groups. The experimental group received 46 cases of medical bio-protein glue group and 48 cases of control group did not use medical bio-protein glue. The drainage volume, Total drainage and subcutaneous effusion occurred, and statistical analysis of the two groups. Results The drainage volume of medical bio-protein glue group was (83.2 ± 10.9) ml on the first postoperative day, which was significantly lower than that of the control group (190.2 ± 36.5) ml, the difference was statistically significant (P <0.05) The drainage volume was (180.8 ± 30.1) ml, which was significantly lower than that of the untreated group (448.1 ± 84.2) ml, the difference was statistically significant (P <0.05). The incidence of subcutaneous effusion in the experimental group was 10.87% 5/46), which was significantly lower than 33.33% (16/48) in the unused bioprotein group. Conclusion The medical bio-protein chamber can effectively control the wound bleeding, close the lymphatic vessels, reduce the wound drainage, reduce the incidence of subcutaneous effusion, in the prevention and treatment of modified radical mastectomy after subcutaneous fluid has a good clinical value.