Genetic architecture, epigenetic influence and environment exposure in the pathogenesis of Autism

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：sun806318188

【摘要】

：

Autism spectrum disorder(ASD) is a spectral neurodevelopment disorder affecting approximately 1% of the population. ASD is characterized by impairments in recip

【作者】

：

YU Li WU YiMing WU Bai-Lin

【机构】

：

Children',sHospitalofFudanUniversity,InstitutesofBiomedicalScience,ClaritasGenomics

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2015年10期

【关键词】

：

表观遗传学遗传结构环境暴露发病机制孤独 DNA甲基化非编码RNA 基因组学 autism spectrum disorder genetic arc

【基金项目】

：

This work was supported by grants from the National Basic Research Program of China （973 Program, 2010CB529601, 2013CB945404）.

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Autism spectrum disorder(ASD) is a spectral neurodevelopment disorder affecting approximately 1% of the population. ASD is characterized by impairments in reciprocal social interaction, communication deficits and restricted patterns of behavior. Multiple

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