A single mutation in the PBC loop of VP2 is involved in the in vitro replication of infectious burs

• 作 者: Xiaole Qi Xiang Gao Zhen Lu Li
• 机 构: DivisionofAvianInfectiousDiseases,JiangsuCo-innovationCenterforPreventionandControlofImportantAnimal
• 出 处: 中国科学：生命科学英文版
• 发表日期: 2016年7期
• 关键词: 传染性法氏囊病病毒 体外复制 PBC VP2 变参 可靠性增长试验 IBDV 中等毒力 infectious bursal disease virus （IBD
• 基金项目: Acknowledgements This work was supported by the National Natural Science Foundation of China （31430087）, the Scientific and Technological Research Project of Harbin （2014AB3AN058）, the Special Fund fo

To test whether amino acid mutations in the PBC and PHI loops of VP2 are involved in the replication and virulence of infectious bursal disease virus（IBDV）, a pair of viruses, namely the moderately virulent IBDV（rG x-F9VP2） and the attenuated strain（rGt）,