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目的观察生脉散辨证加减佐治小儿心肌炎的临床疗效及不良反应。方法选取医院2013年3月-2015年3月收治的小儿心肌炎患者60例,随机分为常规西药组与中西药联合组各30例,对比2组临床疗效及不良反应。结果中西药联合组的总有效率明显高于常规西药组(P<0.05)。中西药联合组治疗后肌酸激酶(CK)、CK-MB及羟基丁酸脱氢酶(HBDH)与常规西药组相比均显著降低(P<0.05)。2组患者均未发生明显消化道症状及肝肾功能等不良反应。结论生脉散辨证加减佐治小儿心肌炎的临床疗效显著,不良反应发生率较低,安全性较高,值得推广。
Objective To observe the clinical curative effect and adverse reactions of Shengmaisan syndrome differentiation and treatment of pediatric myocarditis. Methods Sixty children with pediatric myocarditis admitted to our hospital from March 2013 to March 2015 were randomly divided into two groups, 30 cases in each group. The clinical efficacy and adverse reactions were compared between the two groups. Results The total effective rate of the combination group was significantly higher than that of the conventional western medicine group (P <0.05). The levels of creatine kinase (CK), CK-MB and hydroxybutyrate dehydrogenase (HBDH) in the combination group were significantly lower than those in the conventional western medicine group (P <0.05). Two groups of patients did not occur obvious gastrointestinal symptoms and liver and kidney function and other adverse reactions. Conclusion Shengmaisan syndrome differentiation and treatment of children with myocarditis marked clinical efficacy, low incidence of adverse reactions, high safety, it is worth promoting.