Localization and role of metabotropic glutamate receptors subtype 5 in the gastrointestinal tract

• 作 者: Andrea Ferrigno Clarissa Berar
• 机 构: DepartmentofInternalMedicineandTherapeutics（CellularandMolecularPharmacologyandToxicology）
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2017年25期
• 关键词: Metabotropic glutamate 受体子类型 5 食管 肠 肝 胰 Metabotropic glutamate receptor subtype
• 基金项目: Supported by Italian ministry of University,Research and Instruction

Metabotropic glutamate receptor subtype 5(mGluR5) is a Group I mGlu subfamily of receptors coupled to the inositol trisphosphate/diacylglycerol pathway. Like other m Glu R subtypes, mGluR5 s contain a phylogenetically conserved, extracellular orthosteric