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英国研究人员通过操控单个蛋白,实现了年老实验鼠的胸腺再造,这是科学家们首次成功实现哺乳动物活体器官的再生。结果表明,再生器官与年轻老鼠体内的器官拥有同样结构。研究人员在4月9日出版的《发育》杂志上指出,最新研究有望为免疫系统受损和胸腺发育相关的遗传病患者提供新疗法。胸腺位于心脏附近,能够产生重要的免疫细胞,但也会随年龄增大而衰退,这也是为什么年龄越大的人越容易患流感的原因。新研究中,爱丁堡大学医学研究理事会再生医学中心的研究人员靶向了实验鼠体内一个由胸腺细胞产生的蛋白FOXN1。这种蛋白有助于控制重要的细胞如何
British researchers through the control of a single protein, to achieve the thymus reconstruction of aged mice, which is the first time scientists successfully mammalian living organ regeneration. The results show that organs in regenerative organs have the same structure as the organs in young mice. Researchers in the April 9 issue of “Development” magazine pointed out that the latest research is expected to provide new therapies for those with genetic diseases associated with impaired immune system and thymus development. The thymus, located near the heart, produces important immune cells, but also declines with age, which explains why older people are more likely to get flu. In the new study, researchers from the Regenerative Medicine Center of the Medical Research Council of Edinburgh University targeted a mouse thymocyte-derived protein FOXN1 in mice. This protein helps control how important cells are