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１６例肝细胞性肝癌伴有肝外转移病灶的患者，用~（９９ｍ）Ｔｃ－吡哆－５甲基色氨酸（~（９９ｍ）Ｔｃ－ＰＭＴ）作全身显像，以观察肝外病灶的放射性浓聚。其中骨转移９例，肺转移６例，纵隔软组织转移１例。静脉注射５５５ＭＢｑ（１５ｍＣｉ）~（９９ｍ）Ｔｃ－ＰＭＴ后，先按常规方法作肝显像，并在１、２或３ｈ后追加全身显像或避开肝胆道加摄局部片。本组１６例中８例转移病灶表现为异常放射性集积，病灶分别位于胸骨柄、胸椎、股骨颈、肺及纵隔等相应部位。检测阳性率为５０．０％。由于~（９９ｍ）Ｔｃ－ＰＭＴ肝显像的组织特异性高，对疑及肝细胞癌肝外转移的患者，可用本方法初筛搜寻病灶。
Sixteen patients with hepatocellular carcinoma accompanied by extrahepatic metastases were subjected to whole body imaging with ~ (99m) Tc-pyridoxine-5-methyltryptophan (~ (99m) Tc-PMT) Of the radioactive concentration. There were 9 cases of bone metastasis, 6 cases of lung metastasis and 1 case of mediastinal soft tissue metastasis. After intravenous injection of 555MBq (15mCi) ~ (99m) Tc-PMT, hepatic imaging was performed according to the conventional method. Whole body imaging was performed after 1, 2 or 3 hours or part of liver and gallbladder was removed. The group of 16 cases of 8 cases of metastatic lesions showed abnormal radioactive accumulation, lesions were located in the sternum, thoracic vertebra, femoral neck, lung and mediastinal and other corresponding parts. The positive rate was 50.0%. Due to the high tissue specificity of ~ (99m) Tc-PMT liver imaging, this method can be used to screen for lesions in patients suspected of extrahepatic metastasis of hepatocellular carcinoma.