PKD3 promotes metastasis and growth of oral squamous cell carcinoma through positive feedback regula

• 作 者: Bomiao Cui Jiao Chen Min Luo Yiying Liu Hongli Chen Die Lü Liwei Wang Yingzhu Kang Yun Feng Libin Huang Ping Zhang
• 机 构: StateKeyLaboratoryofOralDiseases&NationalClinicalResearchCenterforOralDiseases&WestChinaHosp
• 出 处: 国际口腔科学杂志:英文版
• 发表日期: 2021年1期
• 基金项目: supported by the National Natural Science Foundations of China(grant nos.81802717 and 81372892).

Oral squamous cell carcinoma(OSCC)has a high incidence of metastasis.Tumour immunotherapy targeting PD-L1 or PD-1 has been revolutionary;however,only a few patients with OSCC respond to this treatment.Therefore,it is essential to gain insights into the mo