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血栓形成及血栓栓塞性血管闭塞疾病的高度发病率和死亡率要求提供新的更有效的治疗药物。手术摘除血栓疗法仅适用于某些病例,有一定局限性。抗凝血疗法只能预防血栓进一步发展,靠体内自发溶纤维蛋白作用消除一些小的血栓,对急性的大的动静脉闭塞效果极差。近十年来发展了一些溶血栓药物,能使血栓溶解,许多场合可代替外科手术
The high morbidity and mortality of thromboses and thromboembolic vascular occlusions require new, more effective treatments. Surgical removal of thrombus therapy is only applicable in some cases, there are some limitations. Anticoagulant therapy can only prevent the further development of thrombus, eliminate some small thrombus by the role of spontaneous fibrinolytic effect in the body, very poor effect on acute large arteriovenous occlusion. In the recent ten years, a number of thrombolytic drugs have been developed that can dissolve thrombolytic drugs and can replace surgery in many occasions