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目的探讨视网膜母细胞瘤(RB)局部浸润和远处转移的MRI和CT影像学表现特征。设计回顾性病例系列。研究对象14例伴有局部浸润和远处转移的RB患者。方法回顾性分析14例患者的MRI和CT影像学表现,包括直接浸润的方式、远处转移的部位、范围、信号和强化特征。主要指标MRI和CT表现。结果 14例患者中12例存在局部浸润,影像学表现为肿瘤沿视神经向后蔓延(11例),或侵犯眼周组织和邻近眶骨(1例)。14例患者中9例出现中枢神经系统转移病灶,3例发生骨转移,3例发生颈部淋巴结转移,2例于腮腺区见转移病灶,最常见的转移部位是中枢神经系统。结论 MRI或CT影像学检查可以及时发现RB远处转移的病变,为临床治疗提供依据。
Objective To investigate the MRI and CT imaging features of retinoblastoma (RB) with local infiltration and distant metastasis. Design retrospective case series. The study included 14 patients with RB who had local infiltration and distant metastasis. Methods The MRI and CT findings of 14 patients were retrospectively analyzed, including the direct infiltration method, the location, range, signal and enhancement features of distant metastasis. The main indicators of MRI and CT performance. Results Twelve of the 14 patients had local infiltrates. The imaging findings were that the tumor spread backward along the optic nerve (11 cases), or the periocular tissue and the adjacent orbital bone (1 case). Nine of 14 patients had central nervous system metastases, 3 had bone metastases, 3 had cervical lymph node metastases, 2 had parotid gland lesions and the most common metastatic site was the central nervous system. Conclusion MRI or CT imaging can detect the distant metastasis of RB in time and provide the basis for clinical treatment.