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以感染破伤风的小鼠作神经功能损伤的动物模型，用神经生长因子（Ｎｅｒｖｅ ｇｒｏｗｔｈ ｆａｃｔｏｒ，ＮＧＦ）进行肌注治疗。结果显示，实验组（ＮＧＦ Ａ、Ｂ组）小鼠存活率明显高于对照组．Ｐ＜０． ０１，表明 ＮＧＦ具有促进感染破伤风小鼠修复神经损伤、恢复运动功能的作用．该结果对ＮＧＦ的临床应用提供了基础。
The tetanus-infected mice were used as animal models of neurological impairment and treated with intramuscular injection of Nerve growth factor (NGF). The results showed that the experimental group (NGF A, B group) mice survival was significantly higher than the control group. P <0. 01, indicating that NGF can promote tetanus infection in mice repair nerve injury, restore motor function. This result provides the basis for the clinical application of NGF.