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目的探讨运动训练对冠心病患者血浆同型半胱氨酸(Hcy)水平的影响。方法将148例冠心病患者分为康复组81例及药物组67例,均给予基础药物治疗和冠心病饮食指导,康复组患者增加运动训练;药物组同时应用叶酸、维生素B_(12)治疗。结果经12周的治疗,2组Hcy水平均明显低于治疗前(P<0.05);组间比较,差异无统计学意义(P>0.05)。康复组心功能及生活质量方面较药物组有明显改善(P<0.05)。结论心脏康复治疗可明显降低冠心病患者Hcy水平,改善心功能状态,提高患者生活质量。
Objective To investigate the effect of exercise training on plasma homocysteine (Hcy) levels in patients with coronary heart disease. Methods 148 patients with coronary heart disease were divided into rehabilitation group (n = 81) and drug group (n = 67). Both groups were given basic drug therapy and coronary heart disease diet guidance. The rehabilitation group were given exercise training. The medication group was also treated with folic acid and vitamin B_ (12). Results After 12 weeks of treatment, the Hcy levels in both groups were significantly lower than those before treatment (P <0.05). There was no significant difference between the two groups (P> 0.05). Rehabilitation group heart function and quality of life than the drug group was significantly improved (P <0.05). Conclusions Cardiac rehabilitation treatment can significantly reduce Hcy in patients with coronary heart disease, improve cardiac function and improve the quality of life of patients.