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目的:比较分析子宫肌瘤患者应用不同剂量米非司酮治疗的临床效果。方法:随机选择2015年10月至2017年1月我院收治的60例子宫肌瘤患者为研究对象,按照计算机数表法均分为两组,即对照组与观察组,各30例。对照组患者给予大剂量米非司酮(25mg/d)治疗,观察组患者给予小剂量米非司酮(12.5mg/d)治疗,统计比较两组患者治疗前后子宫肌瘤体积与子宫体积变化情况。结果:治疗前,两组患者子宫肌瘤体积、子宫体积比较,不具明显差异(P>0.05);治疗后,两组患者子宫肌瘤体积、子宫体积均缩小,且观察组患者明显小于对照组患者,组间比较差异具有统计学意义(P<0.05)。结论 :子宫肌瘤患者应用小剂量米非司酮治疗的临床效果更好,能够明显缩短患者子宫肌瘤体积,改善患者症状,是一种值得应用与推广的治疗方式。
Objective: To comparatively analyze the clinical effect of different doses of mifepristone in patients with uterine fibroids. Methods: Sixty patients with uterine fibroids admitted to our hospital from October 2015 to January 2017 were randomly selected and divided into two groups (control group and observation group), 30 cases in each group. Patients in the control group were treated with high dose of mifepristone (25mg / d), and patients in the observation group were treated with low dose mifepristone (12.5mg / d). The changes of uterine fibroids volume and uterine volume before and after treatment were compared between two groups Happening. Results: Before treatment, the uterine fibroids volume and uterine volume of the two groups were not significantly different (P> 0.05). After treatment, the uterine fibroids volume and uterine volume of both groups were reduced, and the observation group was significantly smaller than the control group Patients, the difference between the groups was statistically significant (P <0.05). Conclusion: The application of low dose mifepristone in patients with uterine fibroids has better clinical effect, which can significantly shorten the volume of uterine fibroids and improve the symptoms of patients. It is a treatment that is worthy of application and promotion.