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本文报告114例糖尿病人的血浆凝血因子Ⅷ促凝活性及相关抗原、抗凝血酶Ⅲ、纤维蛋白原浓度和ADP及瑞斯托霉素诱导的血小板聚集功能。结果表明糖尿病人的凝血因子Ⅷ促凝活性及相关抗原和纤维蛋白原浓度明显高于正常组,有血管病变者增高更为显著;糖尿病人无大血管病组抗凝血酶Ⅲ明显高于有大血管病组和正常组。提示上述改变与糖尿病血管病变的发生有关。
This article reports the coagulation factor Ⅷ procoagulant activity and related antigens, antithrombin Ⅲ, fibrinogen concentration and ADP and ristocetin induced platelet aggregation in 114 cases of diabetic patients. The results showed that coagulation factor Ⅷ procoagulant activity of diabetic patients and related antigen and fibrinogen concentrations were significantly higher than the normal group, with vascular lesions increased more significantly; diastolic blood group patients with diabetes mellitus antithrombin Ⅲ was significantly higher than Large vascular disease group and normal group. Suggesting that the above changes and the occurrence of diabetic vascular disease.