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肝性脑病是各型重症肝炎的常见并发症,它的发病机理是致脑病因素和诱发因素综合作用的结果。慢性重症肝炎尤其在伴有门腔侧枝循环者,氨中毒可能是引起肝性脑病的重要因素,而在急性和亚急性重症肝炎,肝性脑病的发生可能与假性神经递质的毒性、氨基酸代谢紊乱等关系更为密切。因此,肝性脑病的治疗应采取针对发病机理、纠正代谢障碍和恢复正常大脑功能的综合性措施。
Hepatic encephalopathy is a common complication of various types of severe hepatitis, and its pathogenesis is the result of a combination of encephalopathy and predisposing factors. Chronic severe hepatitis, especially associated with collateral circulation, ammonia poisoning may be an important cause of hepatic encephalopathy, and in acute and sub-acute severe hepatitis, hepatic encephalopathy may occur with the false neurotransmitter toxicity, amino acids Metabolic disorders and other relations more closely. Therefore, the treatment of hepatic encephalopathy should take a comprehensive approach to the pathogenesis, correct metabolic disorders and restore normal brain function.