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目的观察葡萄糖酸锌治疗小儿轮状病毒性肠炎的效果。方法选取医院收治的小儿轮状病毒肠炎患儿115例为研究对象,按治疗方式不同分为观察组55例和对照组60例。入院后均接受积极的治疗,对照组采用蒙脱石散剂、益生菌等紧急治疗,口服补盐液纠正电解质失衡等治疗;观察组在此基础上加用葡萄糖酸锌治疗。观察比较2组患儿的治疗效果、临床症状缓解时间及治疗前后心肌酶谱变化情况。结果经治疗后,观察组总有效率为96.36%,高于对照组的81.67%,差异有统计学意义(P<0.05)。观察组大便次数、大便形状恢复正常时间均短于对照组(P<0.05)。治疗后,2组患儿的心肌酶谱较治疗前有改善(P<0.05)。结论葡萄糖酸锌辅助治疗小儿轮状病毒性肠炎的效果显著,有利于改善患儿的临床症状,值得临床推广应用。
Objective To observe the effect of zinc gluconate on rotavirus enteritis in children. Methods A total of 115 cases of children with rotavirus enteritis admitted to the hospital were selected as study subjects, and divided into observation group (55 cases) and control group (60 cases) by treatment method. After admission, all patients received active treatment. In the control group, montmorillonite powder and probiotics were used for emergency treatment. Oral salt solution was used to correct electrolyte imbalance. The observation group was treated with zinc gluconate. The effects of treatment, clinical symptom relief and changes of myocardial enzymes before and after treatment were observed and compared in two groups. Results After treatment, the total effective rate of the observation group was 96.36%, which was higher than that of the control group (81.67%), the difference was statistically significant (P <0.05). The stool frequency and stool shape in the observation group returned to normal shorter than those in the control group (P <0.05). After treatment, myocardial enzymes in both groups improved compared with those before treatment (P <0.05). Conclusion Zinc gluconate adjuvant treatment of pediatric rotavirus enteritis has a significant effect, which is helpful to improve the clinical symptoms of children and is worthy of clinical application.