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某些分子学标志如Ig重链及T细胞受体基因重排对检测恶性淋巴细胞疾患的克隆性细胞群体至关重要。作者采用多聚酶链反应(PCR)及Southern印迹杂交技术对恶性淋巴瘤患者外周血干细胞采集物及其移植(PBSCT)前后残余淋巴瘤细胞进行分
Certain molecular markers such as Ig heavy chain and T cell receptor gene rearrangements are crucial for detecting clonal populations of malignant lymphoid disorders. The authors used polymerase chain reaction (PCR) and Southern blot hybridization in patients with lymphoma of peripheral blood stem cell collection and transplantation (PBSCT) before and after the residual lymphoma cells were divided