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目的：探讨乳腺癌保乳手术加根治性放疗的治疗原则，观察近期疗效。方法：２０例乳腺癌患者施行了肿瘤切除和腋淋巴结清扫术，手术后２～４周接受放疗。外照射用对穿切线野照射全乳腺５０Ｇｙ／５周，瘤床部位组织间插植１９２Ｉｒ针管，一次性放疗８Ｇｙ／１．０～１．５ｃｍ，或用电子束２Ｇｙ／次，共８次。如患者乳房肿瘤位于乳房乳晕区或腋淋巴结阳性，则内乳淋巴结及锁骨区接受放疗。平均随访时间为１４个月。结果：２０例患者全部存活，无１例出现局部复发，无放疗反应，外形满意。只有１例Ｔ４Ｎ１患者在治疗后１８个月出现骨转移。结论：早期乳腺癌患者接受保乳手术加根治性放疗可以取得满意的临床效果，该法可成为早期乳腺癌的常规治疗方法
Objective: To explore the principles of breast cancer breast-conserving surgery plus radical radiotherapy and observe the short-term curative effect. METHODS: Twenty patients with breast cancer underwent tumor resection and axillary lymph node dissection. Radiotherapy was performed 2 to 4 weeks after surgery. The irradiation was performed with a tangent field irradiated with 50 Gy/5 weeks of the entire breast, and a 192Ir needle was inserted between the tumor bed tissues, and 8Gy/1.0 to 1.5 cm of radiation was applied at one time, or 2Gy/time with an electron beam, for a total of 8 times. If the patient’s breast tumor is located in the areola of the breast or if the axillary lymph node is positive, the internal mammary lymph node and clavicular region receive radiotherapy. The average follow-up time was 14 months. RESULTS: All 20 patients survived. No local recurrence occurred, no radiotherapy response and satisfactory appearance. Only 1 patient with T4N1 had bone metastases 18 months after treatment. Conclusion: Breast-conserving surgery combined with radical radiotherapy can achieve satisfactory clinical results in early breast cancer patients. This method can be a routine treatment for early-stage breast cancer.