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临床上长期投与糖皮质激素制剂(下称类甾醇制剂)对血液血管系统、消化系统和神经系统均有影响。作者在减量使用类甾醇制剂时,为了减轻副作用,投与桂枝茯苓丸。实验用Wistar系雄性大白鼠,每组3～5只,在相同条件下重复实验三次。用倍他米松磷酸二钠,上午9～10对投与,一日一次,连续七日。后胶肌肉注射0.8mg/kg。对照组用生理盐水,同样投与。还投与桂枝茯苓丸(桂皮末、牡丹皮末、芍药末、茯苓末、桃仁末的等份混合粉末)。为了使实验材料规格化,对主要成分定量化。
Clinical long-term administration of glucocorticoid preparations (hereinafter referred to as steroids) has an effect on blood vasculature, digestive system and nervous system. In reducing the use of steroid preparations, the authors administered Guizhi Fuling Pills to reduce side effects. Wistar male rats in the experiment were used in groups of 3 to 5, and the experiment was repeated three times under the same conditions. With betamethasone disodium phosphate, 9 to 10 pairs in the morning, once a day, for seven consecutive days. Post-gel intramuscular injection of 0.8 mg/kg. The control group was administered with saline as well. Guizhi Fuling Pills (mixed powders of cinnamon, moutan, end of peony, end of peony, and end of peach kernel) were also administered. In order to normalize experimental materials, the main components were quantified.