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应用平衡法门控心血池显像对20例正常人和43例冠心病患者(心绞痛28例.心肌梗塞15例)进行左心室舒张功能检测。结果提示,对于反映冠心病的左室舒张功能受损,峰充盈率(PFR)是一个较灵敏的指标,并可以反映缺血性心肌受损的严重程度。快速充盈分数(RFF)和房缩充盈分数(AFF)对于评价冠心病左室舒张功能也有重要价值,目前还很少有报道。冠心病组的PFR与RFF、AFF有一定相关性(分别为r=0.51;P<0.0005,r=-0.42;P<0.0025)。舒张功能指标的联合应用可以提高检测冠心病的敏感性。
The left ventricular diastolic function was measured in 20 normal subjects and 43 patients with coronary heart disease (angina pectoris in 28 cases and myocardial infarction in 15 cases) by balanced gated blood pool imaging. The results suggest that peak perfusion (PFR) is a more sensitive indicator of left ventricular diastolic dysfunction reflecting coronary heart disease and may reflect the severity of ischemic myocardial damage. Rapid filling fraction (RFF) and systolic filling fraction (AFF) for the evaluation of left ventricular diastolic function of coronary heart disease is also of great value, is still rarely reported. Coronary heart disease group PFR and RFF, AFF have a certain correlation (r = 0.51; P <0.0005, r = -0.42; P <0.0025). The combination of diastolic function index can improve the sensitivity of detecting coronary heart disease.