梅毒螺旋体抗体快速血浆反应素试验法检测自愿咨询者的梅毒抗体结果分析

来源 :中国卫生检验杂志 | 被引量 : 0次 | 上传用户:you3880066
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目的了解2011年-2015年仪征市自愿咨询检测(VCT)门诊就诊者的梅毒感染状况,为预防和干预提供科学依据。方法用梅毒螺旋体抗体快速血浆反应素试验(RPR)检测2 295人次,并分析RPR法检出的阳性者与性别、年龄和文化程度的关联。结果 RPR法检测2 295人次,检出阳性894例,阳性率为38.95%。梅毒抗体阳性率女性为45.41%,男性为33.33%,不同性别间阳性率差异有统计学意义(P<0.01)。<20岁、20岁~40岁和>40岁梅毒抗体阳性率分别为38.71%、38.48%和39.29%,不同年龄组间的阳性率差异无统计学意义(P>0.05)。文化程度大专以下的梅毒抗体阳性率为40.23%;大专及以上者为35.53%,不同文化程度人群间的梅毒抗体阳性率差异有统计学意义(χ2=4.011,P<0.05)。结论 RPR法检出的梅毒抗体阳性率女性显著高于男性,文化程度大专以下的显著高于大专及以上。应加强高危人群监测,开展宣传教育,从而有效遏制梅毒在人群中的传播。 Objective To understand the status of syphilis infection among VCT patients in Yizheng City from 2011 to 2015 and provide a scientific basis for prevention and intervention. Methods Twenty-one and 295 people were tested by the Rapid Plasma Assay of Treponema pallidum antibody (RPR), and the correlation between the positive and the sex, age and education level analyzed by RPR was analyzed. Results There were 2 295 RPR tests, of which 894 were positive. The positive rate was 38.95%. The positive rate of syphilis antibody was 45.41% in women and 33.33% in males. The positive rate of syphilis was statistically significant (P <0.01). The positive rates of syphilis antibodies in patients aged <20 years, 20-40 years and> 40 years were 38.71%, 38.48% and 39.29%, respectively. There was no significant difference in the positive rates of syphilis among different age groups (P> 0.05). The positive rate of syphilis antibody was 40.23% with college education and 35.53% with college education or above. The positive rate of syphilis antibody among different education groups was statistically significant (χ2 = 4.011, P <0.05). Conclusions The positive rate of syphilis antibody detected by RPR method is significantly higher than that of men. The educational level below tertiary level is significantly higher than that of tertiary level and above. Monitoring of high-risk groups should be strengthened and publicity and education conducted so as to effectively stop the spread of syphilis among the population.
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