Upregulation of Nogo receptor expression induces apoptosis of retinal ganglion cells in diabetic rat

• 作 者: Xuezheng Liu Zhongfu Zuo Wanpe
• 机 构: DepartmentofAnatomy,ScientiifcExperimentalCenter
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2014年8期
• 关键词: 视网膜神经节细胞 NOGO受体 神经细胞凋亡 糖尿病大鼠 受体表达 诱导 RNA干扰 大鼠模型 nerve regeneration diabetes mell
• 基金项目: supported by the National Natural Science Foundation of China,No.31140072,81300931,the Liaoning Provincial Department of Science and Technology Project,No.2011225015,the Natural Science Foundation of

The Nogo receptor is an essential factor for neuronal apoptosis, but the changes in Nogo receptor expression in the retina and the effects of the Nogo receptor on retinal ganglion cell apoptosis in diabetes mellitus remain unclear. We found that Nogo rece