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本文根据孕期合理使用抗生素的原则,将经常使用的抗生素分成三组,第一组为孕妇忌用,见表一.氨基糖苷类抗生素对成人的毒性作用主要是耳毒性和肾脏损害.氨基糖苷类抗生素可通过胎盘,羊水中浓度是母血平均浓度的30~60%.已有报道孕妇使用氨基糖苷类抗生素后发生严重的宫内耳损伤,而且还有发生肾脏毒性的危险(虽尚未见报道).氨基糖苷类抗生素的致癌作用尚不清楚.大部分抗真菌抗生素对成人有严重不良
This article according to the principle of rational use of antibiotics during pregnancy, the commonly used antibiotics are divided into three groups, the first group of pregnant women hanged, see Table I. Aminoglycoside antibiotics on adult toxicity mainly ototoxicity and kidney damage.Aminoglycosides Antibiotics through the placenta, amniotic fluid concentration is the average concentration of maternal 30-60% .It has been reported in pregnant women with aminoglycoside antibiotics after severe intrauterine ear injury, but also the risk of renal toxicity (although not yet reported) The carcinogenicity of aminoglycoside antibiotics is not clear.Most antifungal antibiotics have serious adverse effects on adults