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目的分析无锡市第五人民医院复发结核患者携带结核分枝杆菌的药敏情况以便为复治病人的治疗提供参考。方法在2011年的结核药敏结果中挑出复发感染的178例菌株,并对结果进行分析。结果①所有标本对一种以上药物耐药率为82.6%,耐药率最高的是异烟肼,最低的是卷曲霉素。②女性患者对大多数药物的耐药率和耐多药发生率明显高于男性,差异有统计学意义。结论复发结核患者的耐药情况不容乐观,唯有加强初始结核患者的治愈率,减少结核病的复发和耐药的产生,这才是预防和控制结核病最有效的方法。
Objective To analyze the susceptibility of Mycobacterium tuberculosis in patients with recurrent tuberculosis in the Fifth People’s Hospital of Wuxi City to provide reference for the treatment of retreatment patients. Methods A total of 178 strains of recurrent infections were picked out in the 2011 susceptibility test for tuberculosis, and the results were analyzed. Results ① The resistance rate of all specimens to more than one drug was 82.6%. The highest resistance rate was isoniazid, while the lowest was capreomycin. ② The resistance rate and multidrug-resistant rate of most patients in female patients were significantly higher than those in men, the difference was statistically significant. Conclusions The drug resistance of patients with recurrent tuberculosis is not optimistic. Only by strengthening the cure rate of initial tuberculosis patients and reducing the recurrence of tuberculosis and drug resistance, this is the most effective way to prevent and control tuberculosis.