经尿道膀胱肿瘤直束绿激光剜除术与等离子电切术的疗效对比研究

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目的探讨经尿道膀胱肿瘤直束绿激光剜除术与等离子电切术在膀胱肿瘤治疗中的疗效及安全性。方法选取2012年3月至2013年9月60例经病理活检证实的非肌层浸润性膀胱癌患者,随机分成两组,每组30例。分别采用经尿道膀胱肿瘤直束绿激光剜除术和经尿道膀胱肿瘤等离子电切术治疗。记录两组围手术期情况及术后3个月、6个月的随访情况,对两组数据进行分析,并作统计学处理。结果本次研究中手术均顺利完成,无闭孔神经反射及膀胱穿孔。直束光剜除术组术中出血量、术后膀胱冲洗时间、术后留置尿管时间及术后住院时间明显小于等离子电切组,差异均有统计学意义(P<0.05)。术后3个月时随访均无复发病例,术后6个月时随访,直束绿激光剜除组无复发病例,等离子电切组有1例复发。结论经尿道膀胱肿瘤直束绿激光剜除术治疗膀胱肿瘤疗效显著,与等离子电切术相比更为安全。 Objective To investigate the curative effect and safety of transurethral resection of bladder tumor with green laser excision and plasma resection in the treatment of bladder cancer. Methods From March 2012 to September 2013, 60 patients with non-muscle invasive bladder cancer confirmed by pathological biopsy were randomly divided into two groups (n = 30 in each group). Transurethral resection of the bladder tumor using green laser excision and transurethral resection of the bladder tumor were performed. The perioperative records of two groups and the follow-up of 3 months and 6 months after operation were recorded. The data of two groups were analyzed and statistically analyzed. Results All the operations were successfully completed in this study, with no obturator nerve reflex and bladder perforation. The amount of intraoperative blood loss, postoperative bladder irrigation time, postoperative indwelling catheterization time and postoperative hospital stay were significantly less than those of plasma tangential group, the difference was statistically significant (P <0.05). There were no recurrences at 3 months after operation. All cases were followed up at 6 months after operation. There was no recurrence in the strangulation group and 1 in the plasma-cut group. Conclusions Transurethral cystadenocarcinoma with direct beam green laser ablation is effective in treating bladder cancer, which is safer than plasma resection.
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