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采用ＴＢＡ法测定小鼠体内脂质过氧化的主要终产物丙二醛（ＭＤＡ）含量。结果显示，小鼠感染弓形虫后的第３天ＭＤＡ含量无明显改变，但于感染后第６天其含量显著升高，此时小鼠体内的超氧化物歧化酶活性降低。表明在急性弓形虫感染的后期，宿主组织遭受氧化损伤严重。上述结果为阐明弓形虫病的病理生理机理增加了新的资料，并为临床上对弓形虫病患者考虑用抗氧化剂进行辅助治疗提供了理论基础。
TBA method was used to determine the content of malondialdehyde (MDA), the major end product of lipid peroxidation in mice. The results showed that there was no significant change of MDA content on the 3rd day after infection with Toxoplasma gondii, but the content of Toxoplasma gondii was significantly increased on the 6th day after infection. At this time, the activity of superoxide dismutase in mice decreased. Suggesting that host tissues suffer severe oxidative damage late in acute Toxoplasma infection. The above results add new information for elucidating the pathophysiological mechanism of toxoplasmosis and provide a theoretical basis for the clinical consideration of the use of antioxidants in the treatment of toxoplasmosis patients.