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急性感染性腹泻为一全球性健康问题。它是发展中国家儿童疾病的主要原因和首要死因。在发达国家,该病死亡率虽低,但发病率高。据流行病学调查,美国人急性胃肠炎仅次于呼吸道感染,居第二位。近十年来关于感染性腹泻性疾病的病因学研究颇有进展。目前,对(0～70%的胃肠炎儿童可确定特异的病原体,而六十年代的分离率仅10～30%。轮状病毒人类轮状病毒(human rotavirus,HRV)首先由Bishop等(1973)利用电镜检查急性胃肠炎患儿十二指肠活检标本时发现。在发展中
Acute infectious diarrhea is a global health problem. It is the leading cause of death and the leading cause of childhood disease in developing countries. In developed countries, the disease mortality rate is low, but the incidence is high. According to epidemiological investigation, the U.S. people have the second most common respiratory infection after acute gastroenteritis. The etiology of infectious diarrheal diseases in the past decade has made considerable progress. Currently, specific pathogens can be identified in 0-70% of children with gastroenteritis, compared with only 10-30% in the 1960s Rotavirus Human rotavirus (HRV) was first identified by Bishop et al ( 1973) electron microscopy of children with acute gastroenteritis duodenal biopsy specimens found in the development