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术后恶心呕吐作为手术后严重并发症，其对患者的心理和生理可产生较大影响，甚至影响患者术后康复。预防和治疗术后恶心呕吐受到了临床医师的广泛关注。抗呕吐药物的应用是目前预防和治疗术后恶心呕吐相对安全、有效的方法。地塞米松为糖皮质激素类药物，该文就单纯地塞米松或地塞米松复合其他抗呕吐药物用于预防术后恶心呕吐进行综述。“,”Postoperative nausea and vomiting(PONV),as a serious complication after surgery,has a great influence on the psychological and physiological of the patients,and may even affect the rehabilitation of patients.How to prevent and treat PONV has been attended by the clinicians,and the application of anti-vom-iting drugs is a safe and effective method.Dexamethasone is a glucocorticoid hormone,and here is to make a review of the prevention of PONV with dexamethasone or dexamethasone combined with other anti-vomiting drugs.