Decrease of GSK3βSer-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model

• 作 者: Shuang DENG Zhi-gang NIE Pu-ji
• 机 构: DepartmentofOrthopedics
• 出 处: 当代医学科学(英文)
• 发表日期: 2019年1期
• 关键词: OSTEONECROSIS of the femoral head GSK3Β PHOSPHORYLATION APOPTOSIS DEXAMETHASONE
• 基金项目: the National Natural Scienee Foundation of China(No.81672154).

Nowadays,the cumulative intake of glucocorticoids has become the most common pathogenic factor for non-traumatic osteonecrosis of the femoral head(ONFH).Apoptosis of osteoblasts is considered as the main reason of ONFH at the molecular level.Glycogen synt