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目的:观察奥曲肽辅助治疗肝硬化食管胃底静脉曲张破裂出血的临床疗效。方法:64例肝硬化食管胃底静脉曲张破裂出血患者,随机分为治疗组(36例)和对照组(28例),在常规禁食、抗感染、抗休克、保肝、纠正电解质紊乱、输血止血等综合治疗基础上,前者应用奥曲肽治疗,后者应用垂体后叶素及硝酸甘油治疗。结果:治疗组显效率80.6%,总有效率为97.2%;对照组显效率53.6%,总有效率为82.2%,2组相比差异有统计学意义(P<0.05)。结论:奥曲肽辅助治疗肝硬化食管胃底静脉曲张破裂出血疗效确切,安全方便。
Objective: To observe the clinical efficacy of octreotide in the treatment of patients with esophageal and gastric variceal bleeding due to cirrhosis. Methods: Sixty-four patients with esophageal and gastric variceal bleeding were randomly divided into treatment group (n = 36) and control group (n = 28). In routine fasting, anti-infective, anti-shock, hepatoprotective, Blood transfusion, hemostasis and other comprehensive treatment based on the former application of octreotide treatment, the latter application of pituitrin and nitroglycerin treatment. Results: The effective rate of the treatment group was 80.6%, the total effective rate was 97.2%. The effective rate of the control group was 53.6%, the total effective rate was 82.2%. There was significant difference between the two groups (P <0.05). Conclusion: The octreotide adjuvant treatment of liver cirrhosis esophageal varices bleeding is effective, safe and convenient.