论文部分内容阅读
目的:探讨雌激素联合米非司酮—米索前列醇对中期妊娠引产的临床疗效。方法:选择2013年1月至2013年12月我院接诊的98例中期妊娠引产患者,随机分为实验组和对照组,每组49例,对照组接受口服米非司酮后阴道上米索前列醇片,实验组口服米非司酮的同时加服戊酸雌二醇片,然后阴道上米索前列醇片。采用SPSS 17.0统计软件利用t检验和x2检验统计方法对两组在患者年龄、胎龄、引产时间、成功引产率、出血量等方面进行比较。结果:实验组的平均引产时间为(9.6±1.9h)明显少于对照组(17.1±2.6h),差异有统计学意义P<0.001。实验组有49例(100%)成功引产,而对照组有44例(89.80%)成功引产,差异有统计学意义P<0.05。实验组平均阴道出血量50ml,明显少于对照组的90ml,差异有统计学意义,P<0.05。结论:雌激素联合米非司酮、米索前列醇在中期妊娠引产时可以缩短引产时间、提高了引产成功率、同时减少了阴道出血量。
Objective: To investigate the clinical efficacy of estrogen combined with mifepristone and misoprostol in induction of labor during the second trimester of pregnancy. Methods: From January 2013 to December 2013 in our hospital, 98 cases of midwifery induction of labor were randomly divided into experimental group and control group, 49 cases in each group. The control group received oral mifepristone vaginal Soprostigmine tablets, the experimental group oral mifepristone plus at the same time to take the valerate valerate tablets, and vaginal misoprostol tablets. SPSS 17.0 statistical software was used to compare the two groups in terms of patient’s age, gestational age, induction of labor, successful induction of labor, amount of bleeding and the like by t-test and x2 test. Results: The average induction of labor in experimental group was (9.6 ± 1.9h) less than that in control group (17.1 ± 2.6h), the difference was statistically significant (P <0.001). In the experimental group, 49 cases (100%) successfully induced labor while 44 cases (89.80%) in the control group successfully induced labor, the difference was statistically significant (P <0.05). The experimental group average vaginal bleeding 50ml, significantly less than the control group 90ml, the difference was statistically significant, P <0.05. Conclusions: Estrogen combined with mifepristone and misoprostol can shorten the time of induction of labor in the induction of labor during the second trimester of pregnancy, improve the success rate of induced labor and reduce the amount of vaginal bleeding.